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A simple, automated device for the precise addition of liquids

机译:简单,自动化的设备,可精确 补充液体

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摘要

Metering liquid reagents into reaction mixtures in a controlled andreproducible manner has often been a problem in syntheticchemistry. Carrying out the real simultaneous addition of two ormore liquid reagents (concurrent additions) is even more inconvenient.Difficulties increase when addition volumes become small,when addition times become long, or when the reagents are corrosiveor air-sensitive. We have constructed and tested an inexpensive,automated device for the slow, precise delivery of liquid reagentsinto laboratory-scale reaction mixtures. Controlled by a standardpersonal computer, this slow adder can accommodate liquidvolumes from hundreds of microlitres to litres and addition timesfrom minutes to days. Its glass and Teflon construction makes ituseful for nearly all reagents. By using multiple slow adders, trueconcurrent addition of several liquids can be easily achieved.
机译:以受控和可再现的方式将液体试剂计量加入反应混合物中通常是合成化学中的问题。真正同时添加两种或多种液体试剂(同时添加)更加不便。当添加量变小时,添加时间变长或对腐蚀性或空气敏感的试剂时,难度会增加。我们已经构建并测试了一种廉价的自动化设备,用于将液体试剂缓慢,精确地输送到实验室规模的反应混合物中。该慢速加法器由标准个人计算机控制,可容纳数百微升至几升的液体体积,数分钟至数天的添加时间。它的玻璃和铁氟龙结构使其几乎可用于所有试剂。通过使用多个慢速添加器,可以轻松实现几种液体的真正并发添加。

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